Innovation and New Inventions
Researchers at Saint Louis University are not only generating new knowledge in their labs and classrooms; they’re taking it into the real world with inventions and novel approaches that have the potential to improve the quality of life for all.
Innovation in St. Louis
SLU is proud to support the St. Louis region, leveraging its assets as a Catholic, Jesuit, Carnegie R1 university to address social and environmental challenges, develop a regional talent pipeline, and forge partnerships that are shaping the future of the city.
- SLU is a founding member of the Cortex Innovation Community, a nationally and internationally recognized urban innovation hub. Cortex houses more than 425 companies, from startups to divisions of Fortune 500 enterprises, at its 200-acre campus, fueling scientific discovery across industry and academia.
- SLU is co-leading research and development for the Advanced Manufacturing Innovation Center St. Louis, which aims to make St. Louis an epicenter for advanced manufacturing.
- SLU is a founding member of the Taylor Geospatial Institute (TGI), which launched in 2022. A first-of-its-kind consortium of eight regional research institutions, TGI is a cornerstone of the efforts to establish St. Louis as a global center for geospatial excellence.
- The SLU Center for Additive Manufacturing (CAM) collaborates with researchers on and off campus to translate ideas and concepts into real prototypes and systems. In 2025, SLU CAM brought Project MFG, a national initiative to elevate the next generation of skilled labor professionals, to St. Louis to host an inaugural additive manufacturing competition where nine local high school teams gained experience in industrial additive manufacturing to prepare them for the future workforce.
Incubating Excellence on Campus
The SLU New Venture Accelerator (SLU NVA) is sponsored by the Chaifetz Center for Entrepreneurship in the Richard A. Chaifetz School of Business. This 14-week accelerator provides SLU founders, including student entrepreneurs, with access to funding, resources and advisors to propel their ideas into reality. Participants are eligible for equity-free investments up to $50,000 through a special accelerator fund created through donor support.
Previous SLU NVA projects by students and faculty researchers include GenAssist, a regenerative biomaterial aimed at treating various muscle conditions, which won an Arch Grant in October 2025.
More About the New Venture Accelerator
Research Commercialization
The SLU Research Innovation Group works alongside SLU researchers to protect the intellectual property and bring their discoveries to the marketplace
During the period from July 1, 2021, to July 1, 2025, there were:
- 89 invention disclosures
- 99 patent applications
- 27 issued patents
- 11 active licenses/options to startup companies
A number of SLU researchers have spun their discoveries into startups. These startups develop a variety of products, including non-opiate painkillers for patients with chronic pain.
Engineering for Humanity
Too often technology is difficult or frustrating to use. The challenges of today demand intuitive technologies designed by researchers who know how best to use them. At SLU, researchers are creating new software and technologies that augment human capability rather than hinder it – technologies for a greater good, designed in collaboration with communities in St. Louis and beyond.
Engineering for Health Care
- Silviya Zustiak, Ph.D., develops a variety of new biomaterials, including hydrogels. These jelly-like materials can be used for the controlled release of drugs and other therapeutics.
- Koyal Garg, Ph.D., develops new strategies for muscle rehabilitation and regeneration in patients who have experienced traumatic injuries. One of these strategies includes the use of multifunctional biomaterials that enhance muscle regeneration and function.
Human-Machine Interfaces
SLU researchers are interested in human-machine interfaces, developing new ways for information to be transferred and new technologies with which humans can seamlessly interact.
- Jenna Gorlewicz, Ph.D., and her students have developed next-generation, multimodal touchscreen experiences that can deliver information through several senses including sight, sound and touch. Applications of this technology include making classroom materials accessible for students with disabilities, including blindness and low vision.
- Yan Gai, Ph.D., studies auditory pathways and interactions between the human brain and technology. Her neuroengineering lab has developed a variety of new technologies, including smart hearing aids.
Programming with a Purpose
SLU researchers have leveraged their expertise in artificial intelligence, big data, cybersecurity and more for the greater good of humanity.
- Abby Stylianou, Ph.D., works with large datasets of images and their metadata, building image-search tools to support the National Center for Missing and Exploited Children, as well as a sensor system that detects plant stress and pathogens on Midwest farms and distributes that data to farmers.
- Open Source with SLU gives SLU students the opportunity to develop software to support ongoing research. The team has created a platform for testing small unmanned aerial systems, a scheduling platform for local homeless shelters and a mobile app that allows users to upload audio and images that demonstrate how religion is lived throughout the St. Louis region.
Inventors and Leaders
The National Academy of Inventors (NAI) is a member organization that brings together academic inventors from across the country and recognizes and encourages their success in patents, licensing and commercialization of new technologies.
Since 2019, two SLU researchers have been inducted into the NAI as fellows, and 16 have been inducted as senior members. In 2025, four SLU faculty were inducted:
- Koyal Garg, Ph.D., for biomaterials treating traumatic muscle injuries
- Silviya Zustiak, Ph.D., for hydrogel-drug fabrication and delivery
- Nicola Pozzi, Ph.D., for clotting disorder treatments and diagnostics
- Enrico Di Cera, M.D., for thrombosis therapeutics
NAI Fellows at SLU

2013 Fellow
Richard Bucholz holds 33 issued US patents reflecting his transformational research in image guided neurosurgery. He invented the Stealth neurosurgical navigation system now marketed by Medtronic, which is now the standard of care in brain and spinal procedures worldwide. Bucholz is a Fellow of the National Academy of Inventors, received the St. Louis Metropolitan Medical Society’s 2019 Award of Merit in 2019, and numerous other prior awards including the Missouri Inventor of the Year Award, the Health Care Hero Award and the James B. Eads Award for the Application of Computer Technology to Neurosurgical Procedures from the St. Louis Academy of Science. He is a diplomate of the American Board of Neurological Surgery and a member of numerous professional organizations, including: the American Association of Neurological Surgeons; the Radiosurgical Society; International Society for Computer-Aided Surgery; and the Society for Minimally Invasive Therapy. He also has a fellowship in the American College of Surgeons.

2019 Fellow
Daniela Salvemini is named on 10 U.S. patents and has had major impact in basic research and drug discovery. She founded BioIntervene, Inc., focused on non-opioid pain relief, and also on future applications in chronic inflammation and neurodegenerative disorders. In 2019, BioIntervene raised $30 million to begin clinical trials. Major NIH and foundation grants have also funded her research. Her awards include: Pharmacia-ASPET Award in Experimental Therapeutics, National Academy of Inventors Fellow, St. Louis Academy of Sciences Fellow, Premio Internazionale Maria Luisa de’ Medici Award, Society for Experimental Biology and Medicine D.C Award, Magna Graecia Prize, Searle Discovery Research Achievement Award, Novartis Prize In Pharmacology. She has 184 peer-reviewed articles, published 34 book chapters and reviewed for such journals as Proceedings of the National Academy of Sciences USA, Nature Medicine, J. Clinical Investigation, Pain, Journal of Neuroscience, Journal of Biological Chemistry, Journal of Pharmacology and Experimental Therapeutics and American Journal of Physiology.
NAI Senior Members at SLU
- Rajeev Aurora, molecular microbiology and immunology
- Tomasz Heyduk, biochemistry and molecular biology
- Yie-Hwa Chang, biochemistry and molecular biology
- David Griggs, molecular microbiology and immunology
- Robert Pasken, meteorology
- William Dannevik, earth, environmental, and geospatial science
- Marvin Meyers, chemistry
- John Walker, pharmacological and physical science
- Adriana Montaño, pediatrics and biochemistry and molecular biology
- John Tavis, molecular microbiology and immunology
- Lynda Morrison, molecular microbiology and immunology
- Tim Randolph, clinical health sciences
- Koyal Garg, Ph.D., biomedical engineering
- Silviya Zustiak, Ph.D., biomedical engineering
- Nicola Pozzi, Ph.D., biochemistry and molecular biology
- Enrico Di Cera, M.D., biochemistry and molecular biology


















